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How to Determine Solubility in Water of Organic Compounds

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One physical property that has links to intermolecular forces is solubility. Acids and amines are more soluble than nonpolar compounds due to H-bonding. Solubility Of Organic Compounds Video Khan Academy To verify that a compound has dissolved add 5 HCl to the NaOH mixture until the solution is acidic to pH paper. . But depending upon the type of bond involved organic compounds may be soluble or not. Look for a precipitate indicating that the water-soluble salt has converted back into the water-insoluble compound. That is polar compounds usually are soluble in water and non-polar compounds are not soluble in water. From this exercise you should learn which functional groups enhance water-solubility and how the size and shape of the organic compound influences water-solubility. If hydrophillic region is stronger than hydrophobic region molecule is soluble. Structure determines the lipophilicity. However bec...